Raman spectroscopy-based classification of selected Acute Lymphoblastic Leukemia molecular subtypes 

A. Adamczyk¹, A. Dorosz¹, P. Leszczenko¹, A. Fatla¹,  S. Kashyrskaya¹, A. Grabacka¹, M. Bartoszek¹, A. M. Nowakowska¹, J. Jakubowska³, A. Pastorczak³, K. Ostrowska³, M. Ząbczyńska³, K. Majzner^1,2, M. Barańska^1,2

¹Jagiellonian University, Faculty of Chemistry, Gronostajowa 2 str. 30-387 Krakow, Poland

²Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics, Bobrzynskiego 14 str. 30-348 Krakow, Poland

³Medical University of Lodz, Department of Pediatrics, Oncology and Hematology, Sporna 36/50 str , 91-738 Lodz, Poland

Is Raman imaging a reliable tool for genetic subtypes discrimination  of B-type acute lymphoblastic leukemia?

P. Leszczenko¹, A. Borek-Dorosz^1,2, A. M. Nowakowska¹, A. Adamczyk¹, S. Kashyrskaya¹, J. Jakubowska³, M. Ząbczyńska³, A.  Pastorczak³, K. Ostrowska³, M. Barańska^1,2, K. M. Marzec⁴, K. Majzner^1,2

¹Jagiellonian University, Faculty of Chemistry, Raman Imaging Group, Gronostajowa 2, 30-387 Krakow, Poland;

²Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Bobrzynskiego 14, 30 348 Krakow, Poland;

³Medical University of Lodz, Department of Pediatrics, Oncology and Hematology, Sporna 36/50, 91-738 Lodz, Poland;

⁴Lukasiewicz Research Network – Krakow Institute of Technology, Zakopiańska 73, 30-418 Krakow, Poland

Protocol for Raman analysis of leukemia cells

A. M. Nowakowska¹, A. Borek-Dorosz^1,2, P. Leszczenko¹, A. Adamczyk¹, A. Pieczara², J. Jakubowska³, K. Ostrowska³, A. Pastorczak³, K. Brzozowski1, M. Barańska^1,2, K. Maria Marzec², K.Majzner^1,2*

¹Faculty of Chemistry, Jagiellonian University, 2 Gronostajowa Street, 30-387 Krakow, Poland

²Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, 14 Bobrzynskiego Street, 30-348 Krakow, Poland

³Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Sporna Street 36/50 Łodz, Poland

Metabolic changes identified in IDH1 and IDH2- mutated transgenic  leukemic cells using Raman imaging

A. M. Nowakowska¹,  P. Laskowska², A. Borek-Dorosz^1,3, J. Stolarska¹, A. Adamczyk¹, P. Leszczenko¹, M. Zasowska², M.Szydłowski², E. Białopiotrowicz², P. Mrówka^2,4, M. Barańska^1,3, K. Majzner^1,3

¹Faculty of Chemistry, Jagiellonian University, 2 Gronostajowa Street, 30-387 Krakow, Poland

²Department of Experimental  Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland

³Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, 14 Bobrzynskiego Street, 30-348 Krakow, Poland

⁴Department of Biophysics, Physiology and Pathophysiology, Medical University of Warsaw, Warsaw, Poland

Form: poster and flash presentation