„Recognition of the true and false resonance Raman optical activity”
We are happy to inform that Prof. Małgorzata Barańska and Prof. Dorota Gryko published an article entitled:
„Recognition of the true and false resonance Raman optical activity” in Angewandte Chemie International Edition
Prof. Baranska, Prof. Gryko and authors demonstrate that reliable recording of RROA of chiral colorful compounds is possible, but only after considering the effect of the electronic circular dichroism (ECD) on the ROA spectra induced by the dissolved chiral compound. We show RROA for a number of model vitamin B 12 derivatives that are chemically similar but exhibit distinctively different spectroscopic behavior. The ECD/ROA effect is proportional to the concentration and dependent on the optical pathlength of the light propagating through the sample. It can severely alter relative band intensities and signs in the natural RROA spectra. The spectra analyses are supported by computational modeling based on density functional theory. Neglecting the ECD effect during ROA measurement can lead to misinterpretation of the recorded spectra and erroneous conclusions about the molecular structure.